Prophylactic removal of titanium osteosynthesis miniplates in patients after midface fractures - A retrospective cohort study.

The aim of the study was to evaluate prophylactic removal of titanium osteosynthesis miniplates in patients after midface fractures. Complaints after fracture treatment and complications after plate removal were analyzed, retrospectively. A total of 205 patients were included. Plate removal was performed in 99 cases. Complaints related to the osteosynthesis material resulted in more frequent plate removal (p < 0.001). Complications were noted in 22 patients after plate removal. Duration of plate removal did not correlate with postoperative complications. In 69 patients, plates were removed without previous symptoms. Of these patients, postoperative complications were recorded in 15 cases. In patients with complaints after osteosynthesis, complications after plate removal occurred in seven (23.3%) patients. Ectropia developed significantly more often with increasing age (p < 0.05). CONCLUSION: Within the limitations of the study it seems that prophylactic plate removal is a treatment option that is not associated with an increased complication rate.

Comparative study between patient specific titanium plates versus conventional miniplates for treatment of mandibular fractures: Randomized clinical trial.

The aim of the study was to evaluate and assess the clinical stability and efficacy of three-dimensional patient-specific computer-guided titanium plates versus conventional mini plates when used for the treatment of mandibular fractures. Patients with isolated mandibular body fractures were assigned randomly into two equal groups. Group I was treated with patient-specific 3D titanium plates and Group II was treated with conventional mini plates. Outcome measurements included patient satisfaction, pain, occlusion, occlusal bite force and fracture gap distance. All parameters were evaluated at one-week and three-month intervals. The operating time was measured during the surgery. A total of 20 patients were included in the study. Group I (n=10) showed higher values of patient satisfaction and lower pain values than Group II (n=10) at both follow-up intervals. The degree of occlusal derangement showed no statistically significant difference between both groups at one week postoperatively, while both groups showed normal occlusion after 3 months. Occlusal bite forces in Group I were significantly higher than Group II at both follow up intervals. The fracture gap distance was statistically insignificant between both groups at both follow up intervals. The operating time was significantly lower for Group I. Within the limitations of the study, it seems that in the treatment of mandibular body fractures patient-specific plates are preferred over conventional mini plates as they provide more stability, higher biting forces and shorter operating time with highly acceptable outcomes and promising results.

Titanium miniplate removal after joint orthodontic-orthognathic surgery treatment: a 10-year retrospective hospital-based audit.

INTRODUCTION: The reported incidence of titanium miniplate removal after orthognathic surgery varies widely, making delivery of risk information to patients problematic. This variation relates to potential biases introduced during the study design, for example, with the pooling of different patient types, creating heterogeneous study samples. This study reduces sampling bias by limiting the cohort to only consecutive orthognathic cases. The primary aim of the study was to identify the incidence of miniplate removal following orthognathic surgery. The secondary aim was to assess the indications and any risk factors for miniplate removal. METHODS: Data from the clinical records of 907 orthognathic surgery cases treated within a centralised oral and maxillofacial hospital service over a 10-year period were collected by two operators and analysed. Every identified case qualified for inclusion. Patient demographics (age, sex, medical comorbidity, smoking), operations (type of surgery, duration, third molar removal, complications) and the indication, timing and site of miniplate removal were analysed. RESULTS: Only 19 patients required postoperative miniplate removal, with the most common indication being infection (63%). There was no significant difference in any of the factors assessed except that significantly more miniplates were removed from female patients (68%) (p<0.001) and from mandibular sites (84.2%) (p=0.003). CONCLUSIONS: The incidence of miniplate removal for this sample was 2.1%. Female sex and miniplate location in the mandible were the only statistically significant risk factors for miniplate removal.

Anclaje esquelético para el tratamiento de las anomalías de clase II y mordida abierta anterior: informe de un caso / Skeletal anchorage for the treatment of class II anomalies and anterior open bite: report of a case

El reporte de este caso tiene como objetivo demostrar la utilidad de los anclajes esqueléticos temporarios como son las miniplacas cigomáticas y los microimplantes "buccal shelf" en el tratamiento ortodóncico, en una paciente de 17 años 10 meses de edad, clase II vertical, dólicofacial, con mordida abierta anterior y aumento de la altura facial inferior. Después de la primera fase de tratamiento, siguiendo la secuencia de arcos para completar la alineación, se utilizaron anclajes esqueléticos extrarradiculares con una mecánica de intrusión con fuerzas elásticas durante 10 meses. Se intruyeron sus piezas posteriores superiores e inferiores y se distalizó la arcada superior, corrigiéndose la oclusión. El mentón retrognático y su perfil convexo mejoraron con la autorrotación de la mandíbula (AU)

The objective of this report case is to demonstrate the usefulness of temporary skeletal anchors such as zygomatic miniplates and buccal shelf microimplants in orthodontic treatment, in a 17-year-old 10-month-old, vertical class II, dollicofacial patient with anterior open bite and increased lower facial height. After the first treatment phase, following the arch sequence to complete the alignment, extra-radicular skeletal anchors were used with intrusion mechanics with elastic forces for 10 months. Its upper and lower posterior pieces were intruded and the upper arch was distalized, correcting the occlusion. e retrognathic chin and its convex profile improved with autorotation of the jaw (AU)

2 mm Conventional Miniplates with Three-Dimensional Strut Plate in Mandibular Fractures.

AIM: The aim of this study was to compare 2 mm conventional miniplates with three-dimensional (3D) strut plates in the treatment of mandibular fractures treated in the Department of Oral and Maxillofacial Surgery of a college in India, during 2012-2015. MATERIALS AND METHODS: All 20 patients with mandible fracture requiring open reduction and internal fixation of the fracture were reported and reviewed in the Department of Oral and Maxillofacial Surgery of the same dental college in India, during 2012-2015. We classified the data according to the gender, age, etiology, fracture site, and method of treatment of the fractures. Fixation done in 10 patients with 2 mm conventional miniplates kept in Group I, while 10 patients with 3D strut miniplate system considered in Group II. RESULTS: Assessment of patient was done under the following parameters with follow-up at regular intervals at 2nd day postoperatively and at 1st, 3rd, and 6th weeks postoperatively: pain, swelling, infection, interincisal mouth opening in millimeters, paresthesia/anesthesia, mobility between fracture fragments, overall occlusion, need for any supplemental fixation, fate of implant, and complications. CONCLUSIONS: 3D titanium miniplates showed similar results when compared to standard titanium miniplates with advantages such as reduction in operative time, ease of placement, and cost-effective over the conventional plate system.

Six-hole versus Four-hole Miniplates in Isolated, Unilateral Angle Fracture of the Mandible.

AIM: The aim of the study was to find the suitable situation for the fixation of "six" hole miniplates in open reduction and internal fixation of displaced and nondisplaced unilateral angle of the mandible fractures. SUBJECTS AND METHODS: Displaced, nondisplaced, simple, compound (linear and noncomminuted) isolated unilateral angle fractures with or without occlusal derangement were included in this study. STATISTICAL ANALYSIS USED: Chi-square test was used for the statistical analysis. RESULTS: The parameters assessed preoperatively and postoperatively were mouth opening, occlusion, neurosensory deficit such as paresthesia, intraoperative time, stability of fragments, and access to the retromolar trigone which showed that the six-hole titanium miniplate was clinically useful in special clinical situations when compared to four-hole titanium miniplate. CONCLUSION: To conclude, six-hole titanium miniplate was clinically useful when compared to four-hole titanium miniplate in the following special clinical situations such as bone loss following extraction of third molar, no posterior occlusion and instability of fracture moderately displaced fracture needs more stability.

Comparative Evaluation of 3d Locking Versus Non-Locking Titanium Miniplates in the Treatment of Mandibular Fracture.

The introduction of 3-dimension systems for the treatment of mandibular fractures and continuity has offered certain advantages over other plating system. The present study was undertaken to compare 2.0 mm 3D titanium locking and non-locking miniplates in the management of mandibular fractures. A prospective study was conducted on 40 patients (20 in each group) of mandibular fractures treated by open reduction and internal fixation. Group A patients underwent osteosynthesis using 2.0 mm 3-D titanium locking miniplates while Group B used non-locking miniplates. Subsequent follow-up was assessed for pain, swelling, infection, paresthesia, malocclusion, mobility between fracture fragments and hardware failure in these patients. Functional occlusion was achieved postoperatively in all the patients. At 12 weeks of the time intervals, significant pain was observed in group B. At 1 week interval, 6 (30%) patients in both groups reported with swelling. Only one (10%) patient in each group had paresthesia which got resolved gradually over a period of 3 months. Infection was observed in only 2 (10%) patient in Group B at 3 months. Only 2 (10%) patient in Group B had hardware failure at 3 months interval. Statistically, there was no significant difference between both the groups at any time interval (p > 0.05). 3D titanium locking miniplates are effective in the treatment of mandibular fractures with lesser overall complications as compared to non-locking miniplates.

Comparing clinical outcomes of using 3 versus 5 titanium miniplates in laminoplasty for multilevel cervical myelopathy: A prospective cohort study.

STUDY DESIGN: Prospective cohort study. OBJECTIVE: The aim of this study was to compare clinical outcomes, radiographic changes, and complications of cervical expansive open-door laminoplasty（EOLP）for cervical multilevel myelopathy, using either 3 or 5 titanium miniplates. SUMMARY OF BACKGROUND DATA: Cervical EOLP is a common and effective operation for cervical myelopathy. Standard procedures utilise either 3 or 5 titanium miniplates; however, no definite conclusion has been given yet on the relationship between clinical outcomes and the quantity of titanium miniplates. METHOD: We performed a prospective study of 92 patients who underwent EOLP with either 3 (n â€‹= â€‹34) or 5 (n â€‹= â€‹58) titanium miniplates at our institution from March 2012 to June 2016. Clinical and radiologic outcomes and complications were compared. RESULT: Compared with the 5 titanium miniplates group, the 3 titanium miniplates group had shorter operation times and less blood loss (P â€‹< â€‹0.05) and needed fewer costs (P â€‹< â€‹0.01) during index hospitalisation. The preoperative cervical curvature angle decreased in both groups and revealed no significant differences. There was no significant difference between the two groups in the Japanese Orthopedic Association (JOA) score, JOA recovery rate, loss of range of motion (ROM), anteroposterior diameter (APD), or spinal canal complications (P â€‹> â€‹0.05). CONCLUSION: Cervical EOLP using 3 titanium miniplates is associated with shorter operation times, less blood loss, and lower operation costs compared with using 5 titanium miniplates. THE TRANSLATIONAL POTENTIAL OF THIS ARTICLE: Expansive open-door laminoplasty (EOLP) is an effective procedure for treating multilevel cervical spondylotic myelopathy. The present study indicated that 3 titanium miniplates could achieve similar clinical outcomes but with shorter operation times, less blood loss and operation costs compared with 5 titanium miniplates. These findings may provide some references for clinical applications.

Posterior open-door laminoplasty secured with titanium miniplates vs anchors: a comparative study of clinical efficacy and cervical sagittal balance.

OBJECTIVE: Posterior open-door laminoplasty (PODL) is a common procedure for treating multilevel cervical spondylotic myelopathy (MCSM). Little information is available regarding the cervical sagittal balance and surgical efficacy of PODL when securing with different methods. Therefore, this study aims to investigate the clinical outcomes and the changes in cervical sagittal parameters and balance associated with PODL secured with titanium miniplates vs anchors. METHOD: A retrospective analysis was performed on the clinical data of 79 patients with MCSM who were treated in our institution from January 2015 to December 2016. Among them, 42 patients were treated by PODL secured with titanium miniplates (group A) and 37 patients by PODL secured with anchors (group B). Surgical time, intraoperative blood loss, hospital stay, hospitalized cost, VAS scores of neck pain, JOA scores, neck disability index (NDI), and improvement rate of spinal neurological function (IRNF) were recorded before surgery and at 12 months after surgery. Before surgery, at 1 month and 2 years after surgery, the following radiological parameters were recorded and compared on the lateral cervical X-ray images: the distance from the vertical axis of C2 sagittal plane to the posterior superior edge of C7 (C2-7 SVA), the inclusion angle of tangent between C2 and C7 trailing edge (C2-7 Cobb angle), and the intersection angle between the upper edge of T1 and the horizontal line (T1 Slope). RESULT: Comparing the two groups, there were no significant differences in surgical time, intraoperative blood loss, hospital stay, VAS, JOA, and NDI scores before surgery (P > 0.05); however, the hospitalized cost of group A were much higher than those of the group B (P < 0.05). At 2 years after surgery in the two groups, there was a significant reduction in VAS and NDI scores (P < 0.05), and JOA scores increased significantly (P < 0.05). In addition, there were no significant differences in VAS, JOA and IRNF between the two groups (P > 0.05); however, NDI scores of group A were better than those of group B (P < 0.05). In radiological parameters, before surgery, the two groups showed no significant differences in C2-7 SVA, C2-7 Cobb angle, and T1 slope (P > 0.05); however, after surgery, C2-7 SVA and T1 slope increased (P < 0.05), while C2-7 Cobb angle decreased (P < 0.05). At 2 years after surgery, the two groups did not differ significantly in C2-7 Cobb angle and T1 slope (P > 0.05), while C2-7 SVA of group A was superior to that of group B (P < 0.05). The difference value of C2-7 SVA measured before and after surgery was correlated negatively with that of NDI scores (P < 0.05). CONCLUSION: PODL secured with titanium miniplates or anchors achieved good clinical efficacy in the treatment of MCSM. However, the patients with miniplates feel a better cervical functional status, while those with anchors spend less on hospitalization. Both methods lead to anteversion of cervical spine, but cervical sagittal balance after miniplates is better than that of anchors.

Chronic headache caused by a titanium fixation plate: Report of two cases.

BACKGROUND: We report two patients with chronic postcraniotomy headache who showed rapid alleviation of pain after removal of titanium miniplates. CASE DESCRIPTION: (Case 1) A 26-year-old woman underwent a right frontal craniotomy and excision of the entire cerebral cavernous malformation. Eleven years later, she developed headache. The titanium plate was removed and the patient presented complete amelioration of headache. (Case 2) A 50-year-old man underwent an aneurysm clipping via the lateral supraorbital approach of the left side. One year later, he complained about throbbing pain. Removing the titanium plate led to complete relief of the headache. CONCLUSION: Titanium miniplate fixation may irritate the deep division of the supraorbital nerve and may cause a chronic headache. Here, we propound the idea that, postcraniotomy, titanium miniplates should not be placed above the temporal fusion line.

In Vitro Effect of 3D Plates Used for Surgical Treatment of Condylar Fractures on Prostaglandin E2 (PGE2) and Thromboxane B2 (TXB2) Concentration in THP-1 Macrophages.

Recent studies have shown promising results concerning the effectiveness of 3D plates in terms of stabilization of condylar fractures. Despite the use of new techniques and new materials, we can still observe certain side effects, including the immune reaction of the body, which may lead to the excessive inflammation. The aim of this paper was to determine how the production of prostaglandin E2 (PGE2) and thromboxane B2 (TXB2) in THP-1 monocytes/macrophages is influenced by the titanium 3D plates and dedicated screws. The experiments were conducted on THP-1 monocytic cell line and macrophages derived from a THP-1cells. The concentrations of PGE2 and TXB2 released were measured by using immunoassay kit. Verification of plate-induced activation of THP-1 monocytes and macrophages and initiation of inflammatory reaction was conducted by flow cytometry. Despite some differences in the content of the implant devices our results showed that these plates did not statistically significantly increase the production of these prostanoids. Osteosynthesis of condylar fractures using 3D titanium mini-plates seems to be a good alternative to traditional plates due to their lack of stimulating the cyclooxygenase-dependent production of prostanoids; limiting the development of inflammatory reactions.

Comparison of Stability of Fracture Segments in Mandible Fracture Treated with Different Designs of Mini-Plates Using FEM Analysis.

AIM: To compare the displacement gap of mandible fracture segments treated with different designs of mini-plates under various loading conditions. MATERIALS AND METHODS: Fracture in the body of mandible was bridged with 15 different designs and configuration of titanium mini-plates. Bite forces were applied at 3 locations, ipsilateral fractured side, contra lateral side and incisor site. 3D finite element methods (FEM) model of mandible was generated using 10 nodal tetrahedral elements. A commercial FE solver was used to solve bone inter fragmentary displacement during loading. RESULTS: Superior position of mini-plates produced better stability than inferior position. Positive bending moments can be reduced by larger plate in lower border in 2 plate system. Results of X mini-plate are comparable to 2 plate configuration. If length of middle portion of plate increased, stability decreased. Number of screws did not affect fracture stability. CONCLUSION: Finite element methods analysis is used to determine the gap between mandible fragments which is otherwise impossible to measure clinically. The results obtained from this study offered us a choice of mini-plate design and configuration for clinical application.

Three-dimensional v/s standard titanium miniplate fixation in the management of mandibular fractures--a randomized clinical study.

PURPOSE: The aim of this study was to compare treatment outcomes using three-dimensional and standard titanium miniplates in the management of mandibular fractures. MATERIAL AND METHODS: A prospective study of 30 patients with mandibular fractures. Patients were randomly categorized into 2 groups with 15 patients in each group; patients in Group I were treated with 2.0 mm 3-dimensional titanium miniplate and screws and patients in Group II were treated with 2.0 mm standard plates and screws. Clinical parameters evaluated were: intra-operative assessment of reduction, intra-operative and post-operative assessment of stability of occlusion, mobility of fracture fragments and need for intermaxillary fixation. Radiographic parameters included pre-operative evaluation of displacement of fracture fragments and post-operative evaluation of bone union and plate fracture at different time intervals. RESULTS: In Group I, 3 patients (20%) and in Group II, 8 patients (53%) had gap between fracture fragments during reduction. Six patients (40%) in Group I and 8 patients (53%) in Group II had mildly deranged occlusion on the 7th post-operative day. Two patients (13%) in Group I and 6 patients (40%) in Group II needed IMF till the end of the 1st month. No patients showed tissue dehiscence at the end of 1st and 3rd month post-operatively. Infection was not observed in any patient post-operatively. Five patients (33%) from Group I had displaced fracture fragments and 10 patients (67%) had severely displaced fracture fragments pre-operatively. Seven (47%) patients from Group II had displaced fracture fragments and 8 (53%) had severely displaced fracture fragments pre-operatively. Nine patients (60%) in Group I and 6 patients (40%) in Group II showed radiographic evidence of bone union after the 3rd month post-operatively. CONCLUSION: The use of 3D miniplate is a viable option for fixation of mandibular fractures routinely. 3D titanium miniplates showed comparable results compared to standard titanium miniplates.

[Guided maxillofacial surgery: Simulation and surgery aided by stereolithographic guides and custom-made miniplates]. / Chirurgie maxillofaciale guidée : simulation et chirurgie assistée par guides stéréolithographiques et miniplaques titane préfabriquées.

We present a new model of guided surgery, exclusively using computer assistance, from the preoperative planning of osteotomies to the actual surgery with the aid of stereolithographic cutting guides and osteosynthetic miniplates designed and made preoperatively, using custom-made titanium miniplates thanks to direct metal laser sintering. We describe the principles that guide the designing and industrial manufacturing of this new type of osteosynthesis miniplates. The surgical procedure is described step-by-step using several representative cases of dento-maxillofacial dysmorphosis. The encouraging short-term results demonstrate the wide range of application of this new technology for cranio-maxillofacial surgery, whatever the type of osteotomy performed, and for plastic reconstructive surgery.

Application of titanium miniplates in reconstruction of laminar roof after a posterior approach in intraspinal tumor surgery / 中国综合临床

Objective To evaluate the surgical technique of titanium miniplates in reconstruction of laminar roof after a posterior approach in intraspinal tumor surgery. Methods From August, 2007 to March, 2009, 11patients underwent intraspinal tumor surgery with osteotomy and reconstruction of laminar roof, titanium miniplates were used for fixing in the re-implantation. There were 2 intramedullary tumors,9 extramedullary tumors. The target of surgery was the cervical spine in 2 cases, the cervicothoracic spine in 4 cases, the thoracic spine in 2 cases, the thoracolumbar spine in 2 cases, and the lumbar spine in 1 cases. The patitens were followed up for 6 months to 2years. Local pain,bony healing and spinal malformation were assessed. Results In the 11 patients, there was no case of dural, nerve root, or spinal cord injury due to laminar roof reconstruction. One patient complained of moderate to severe local pain during follow-up and 2 patients complained of occasional slight pain at the surgical site. No limitation of activity occurred. Bony healing was confirmed radiologically or CT scan in 9 patients. There were no patients demonstrated a new spinal malalignment, and no patients developed stenosis of the spinal canal. Conclusions The reconstruction of the laminar roof using titanium miniplates will benefit the recovery of normal structure of spine,and maintain the stability of spine,and avoid the occurrence of stenosis of the spinal canal.